Cocaine

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.

Also Known As:

Cocaine HCl; Cocaine Hydrochloride; HCl, Cocaine; Hydrochloride, Cocaine; 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-

Pharmalogical Action Categories:

Anesthetics, Local
Dopamine Uptake Inhibitors
Vasoconstrictor Agents

Organic Chemicals: 133
- Aza Compounds: 3
  - Azabicyclo Compounds
    - Tropanes: 1
      - Cocaine: 10317
Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Tropanes: 1
    - Cocaine: 10317
- Bridged-Ring Heterocyclic Compounds
  - Tropanes: 1
    - Cocaine: 10317
  - Heterocyclic Bridged Bicyclo Compounds
    - Azabicyclo Compounds
      - Tropanes: 1
        Cocaine: 10317

Jeroen van de Wetering Selected Research

Jeroen van de Wetering Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure